hepg2 human caucasian hepatocyte carcinoma cell line (ATCC)
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Hepg2 Human Caucasian Hepatocyte Carcinoma Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 29943 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Culture:Article Title: Cytoprotective dihydronaphthalenones from the wood of Catalpa ovata. Article Snippet: Three previously undescribed dihydronaphthalenones, 7-hydroxycatalponol, (4S)-3,4-dihydro-4hydroxy-2-[(2R)-2,3-dihydroxy-3-methylbutylidene]naphthalen-1(2H)-one, and (6S)-5,6-dihydro-6hydroxy-2,2-dimethyl-2H-benzo[h]chromen-4(3H)-one and one phthalide, (±)-3-(5-hydroxy-5-methyl2-oxohex-3-en-1-yl)isobenzofuran-1(3H)-one, were isolated from the wood of Catalpa ovata G. Don (Bignoniaceae), together with six known compounds.. The structures of the previously undescribed compounds were elucidated by interpretation of 1D and 2D NMR data.. The absolute configurations of the dihydronaphthalenones were deduced by analysis of the ECD data and application of Mosher ester methodology. Article Title: Impact of spray-drying and adjuvants addition on antinutrients, phenolics profile and bioactivity of chickpea beverage bases. Article Snippet: Processing plays a crucial role in determining the final properties of plant-based ingredients; therefore, it can be used to enhance their nutritional attributes and biological activities with health-promoting potential.. Scalable unitary operations must preserve product functionality and sensory traits.. Freeze-drying preserves those characteristics but scales harder than spray-drying. Article Title: Furanocoumarins from the Roots of Angelica dahurica with Inhibitory Activity against Intracellular Reactive Oxygen Species Accumulation. Article Snippet: Five new furanocoumarins, dahuribirin H (1), dahuribirin I (2), (2′S)-(+)-5-(2′-hydroxy-3′-methylbut-3′enyloxy)-8-(3′′-methylbut-2′′-enyloxy)psoralen (3), (2′R)(+)-5-(2′,3′-epoxy-3′-methylbutoxy)-8-(3′′-methylbut-2′′enyloxy)psoralen (4), and 5-methoxy-8-((Z)-4′-(3′′-methylbutanoate)-3′-methylbut-2′-enyloxy)psoralen (5), along with 15 known compounds (6−20), were isolated from the roots of Angelica dahurica.. The structures of the new compounds were elucidated by spectroscopic analysis, along with electronic circular dichroism calculations and Mosher ester analysis.. Compounds 3, 4, 11, 13, and 16 reduced H2O2-induced cell death in HepG2 cells and attenuated reactive oxygen species (ROS) formation without showing cytotoxicity, suggesting that these compounds might have cytoprotective effects against H2O2-induced oxidative damage via ROS scavenging activities. |
